{"created":"2023-06-19T09:22:08.630285+00:00","id":749,"links":{},"metadata":{"_buckets":{"deposit":"a90e99d9-54f7-4499-8d52-b7952e839bb2"},"_deposit":{"created_by":4,"id":"749","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"749"},"status":"published"},"_oai":{"id":"oai:auhw.repo.nii.ac.jp:00000749","sets":["86:113"]},"author_link":["4114","4110","4113","4111","4115","4112"],"item_10002_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Quantitative electron-microscopic study on glial cells in contact with the perivascular space in the rat pineal gland : Effects of intracranial surgery"}]},"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"137","bibliographicPageStart":"133","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"青森県立保健大学紀要"},{"bibliographic_title":"Journal of Aomori University of Health and Welfare","bibliographic_titleLang":"en"}]}]},"item_10002_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"神経組織に由来する松果体において、ダリア性支持細胞に松果体除去頭蓋内対照手術(SPX)の影響が見られるか否かを電顕的に検索・比較した。24時間明暗周期、22±2℃の恒温環境で飼育し、5週齢でSPXを行い、術後2週間の暗期開始後4時間で屠殺した正常(NO)群、SPX群の雄性ラット各3匹を用いた。2.5%GAと1%OsO4で固定した後、通常の方法で松果体電顕モンタージュ写真(倍率7,800倍)を作製、血管周囲腔を被覆するダリア性細胞と松果体細胞それぞれの膜の長さと細胞断面数を計測した。血管周囲腔を被覆するダリア性細胞の周長に対する比率は、SPX群(N、X±SE : 33、43.6±3.0%)でNO群(38、58.5士3.1%)よりも有意の低値を示した(t検定:P<0.001)。ダリア性細胞と松果体細胞断面の数的比率には、NO群(47.1±1.9%、52.9±1.9%)で差異は見られなかったが、SPX群(39.5±2.0%、60.5±2.0%)で有意差が見られ(P<0.001)、面細胞の実験群間差も有意であった(P<0.01)。実験成績より、SPXは血管周囲腔を被覆するダリア性細胞の形状や配置に影響し、松果体細胞からの分泌物の血管周囲腔への放出を容易にする可能性が示唆されたが、今後更に微細構造も含めて検討する必要があると考えられた。\nGlial cells in the rat pineal gland of normal and sham-pinealectomized (SPX) groups were examined electron microscopically, 14 days after surgery. The relative lengths of glial cell membrane profiles adjoining the basal lamina of the perivascular spaces were significantly decreased by surgery. The relative numbers of glial cells showed similar tendency. It is suggested that such anatomical rearrangement may facilitate the release of pineal homone(s) into, and influences of regulatory and/or modulatory substances from, the perivascular spaces.","subitem_description_type":"Abstract"}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"国立情報学研究所の「学術雑誌公開支援事業」により電子化されました","subitem_description_type":"Other"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24552/00000743","subitem_identifier_reg_type":"JaLC"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1345-5524","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鈴木, 孝夫"},{"creatorName":"スズキ, タカオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4110","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高橋, 元"},{"creatorName":"タカハシ, ゲン","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4111","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加地, 隆"},{"creatorName":"カチ, タカシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4112","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Takao","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4113","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takahashi, Gen","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4114","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kachi, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4115","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-02-08"}],"displaytype":"detail","filename":"KJ00000683495.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000683495.pdf","url":"https://auhw.repo.nii.ac.jp/record/749/files/KJ00000683495.pdf"},"version_id":"4caf1663-61fc-4c3e-acc7-82a3a1809f45"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"松果体,ダリア性細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"血管周囲腔","subitem_subject_scheme":"Other"},{"subitem_subject":"pineal gland","subitem_subject_scheme":"Other"},{"subitem_subject":"glial cell","subitem_subject_scheme":"Other"},{"subitem_subject":"perivascular space","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_thumbnail":{"attribute_name":"サムネイル","attribute_value_mlt":[{"subitem_thumbnail":[{"thumbnail_label":"KJ00000683495-1.png","thumbnail_url":"/api/files/a90e99d9-54f7-4499-8d52-b7952e839bb2/KJ00000683495-1.png?versionId=115e60ef-9fe9-48a0-a070-ea6b3d0872b4"}]}]},"item_title":"ラット松果体におけるグリア性支持細胞の電顕的研究 : 頭蓋内手術の影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ラット松果体におけるグリア性支持細胞の電顕的研究 : 頭蓋内手術の影響"}]},"item_type_id":"10002","owner":"4","path":["113"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-03-08"},"publish_date":"2010-03-08","publish_status":"0","recid":"749","relation_version_is_last":true,"title":["ラット松果体におけるグリア性支持細胞の電顕的研究 : 頭蓋内手術の影響"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-06-19T09:47:49.046143+00:00"}